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1

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

Gambus, Agnieszka, Jones, Richard C., Sanchez-Diaz, Alberto, Kanemaki, Masato, van Deursen, Frederick, Edmondson, Ricky D., Labib, Karim

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 5.60 MB

english, 2006

2

Replisome Stability at Defective DNA Replication Forks Is Independent of S Phase Checkpoint Kinases

Giacomo De Piccoli, Yuki Katou, Takehiko Itoh, Ryuichiro Nakato, Katsuhiko Shirahige, Karim Labib

Journal:

Year:

2012

Language:

english

File:

PDF, 1.88 MB

english, 2012

3

Targeting the genome stability hub Ctf4 by stapled-peptide design

Wu, Yuteng, Villa, Fabrizio, Maman, Joseph, Dobnikar, Lina, Lau, Yu H, Simon, Aline C, Labib, Karim, Spring, David R, Pellegrini, Luca

Journal:

Angewandte Chemie International Edition

Year:

2017

Language:

english

File:

PDF, 3.14 MB

english, 2017

4

MLP bilinear separation

Richard Labib, Karim Khattar

Journal:

Neural Computing and Applications

Year:

2010

Language:

english

File:

PDF, 837 KB

english, 2010

5

10.1038/15649

Diffley, John F.X., Labib, Karim, Kearsey, Stephen E.

Journal:

Nature Cell Biology

Year:

1999

Language:

english

File:

PDF, 360 KB

english, 1999

6

10.1038/40259

Journal:

Year:

1997

Language:

english

File:

PDF, 36 KB

english, 1997

7

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome

Gambus, Agnieszka, van Deursen, Frederick, Polychronopoulos, Dimitrios, Foltman, Magdalena, Edmondson, Ricky D, Calzada, Arturo, Jones, Richard C, Labib, Karim

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 1.30 MB

english, 2009

8

New insights into the chromosome cycle. Conference on the Replication & Segregation of Chromosomes

de la Cueva-Mendez, Guillermo, Labib, Karim

Journal:

Year:

2008

Language:

english

File:

PDF, 315 KB

english, 2008

9

Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo

Kanemaki, Masato, Sanchez-Diaz, Alberto, Gambus, Agnieszka, Labib, Karim

Journal:

Year:

2003

Language:

english

File:

PDF, 1.35 MB

english, 2003

10

Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast

Sanchez-Diaz, Alberto, Marchesi, Vanessa, Murray, Stephen, Jones, Richard, Pereira, Gislene, Edmondson, Ricky, Allen, Terry, Labib, Karim

Journal:

Nature Cell Biology

Year:

2008

Language:

english

File:

PDF, 3.59 MB

english, 2008

11

Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks

Kanemaki, Masato, Labib, Karim

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 345 KB

english, 2006

12

Replication fork barriers: pausing for a break or stalling for time?

Labib, Karim, Hodgson, Ben

Journal:

Year:

2007

Language:

english

File:

PDF, 203 KB

english, 2007

13

Bring on the phosphatases

Karim Labib, Paul Nurse

Journal:

Current Biology

Year:

1993

Language:

english

File:

PDF, 452 KB

english, 1993

14

rum1: a CDK inhibitor regulating G1 progression in fission yeast

Karim Labib, Sergio Moreno

Journal:

Trends in Cell Biology

Year:

1996

Language:

english

File:

PDF, 2.37 MB

english, 1996

15

Ectopic pregnancy in a uterine perforation site

Anwar H. Nassar, Iman Charara, Abdel Karim Nawfal, Labib Ghulmiyyah, Ihab M. Usta

Journal:

American Journal of Obstetrics and Gynecology

Year:

2009

Language:

english

File:

PDF, 392 KB

english, 2009

16

The Amino-Terminal TPR Domain of Dia2 Tethers SCFDia2 to the Replisome Progression Complex

Hiroko Morohashi, Timurs Maculins, Karim Labib

Journal:

Current Biology

Year:

2009

Language:

english

File:

PDF, 910 KB

english, 2009

17

A key role for the GINS complex at DNA replication forks

Karim Labib, Agnieszka Gambus

Journal:

Trends in Cell Biology

Year:

2007

Language:

english

File:

PDF, 767 KB

english, 2007

18

MCM proteins: evolution, properties, and role in DNA replication

Stephen E. Kearsey, Karim Labib

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1998

Language:

english

File:

PDF, 898 KB

english, 1998

19

Making Connections at DNA Replication Forks: Mrc1 Takes the Lead

Journal:

Year:

2008

Language:

english

File:

PDF, 160 KB

english, 2008

20

Is the MCM2–7 complex the eukaryotic DNA replication fork helicase?

Karim Labib, John F.X Diffley

Journal:

Current Opinion in Genetics & Development

Year:

2001

Language:

english

File:

PDF, 102 KB

english, 2001

21

Cell cycle control of eukaryotic DNA replication

Stephen E Kearsey, Karim Labib, Domenico Maiorano

Journal:

Current Opinion in Genetics & Development

Year:

1996

Language:

english

File:

PDF, 766 KB

english, 1996

22

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

Simon, Aline C., Zhou, Jin C., Perera, Rajika L., van Deursen, Frederick, Evrin, Cecile, Ivanova, Marina E., Kilkenny, Mairi L., Renault, Ludovic, Kjaer, Svend, Matak-Vinković, Dijana, Labib, Karim, C

Journal:

Year:

2014

Language:

english

File:

PDF, 6.78 MB

english, 2014

23

Eukaryotic Replisome Components Cooperate to Process Histones During Chromosome Replication

Foltman, Magdalena, Evrin, Cecile, De Piccoli, Giacomo, Jones, Richard C., Edmondson, Rick D., Katou, Yuki, Nakato, Ryuichiro, Shirahige, Katsuhiko, Labib, Karim

Journal:

Year:

2013

Language:

english

File:

PDF, 3.16 MB

english, 2013

24

Dpb2 Integrates the Leading-Strand DNA Polymerase into the Eukaryotic Replisome

Sengupta, Sugopa, van Deursen, Frederick, de Piccoli, Giacomo, Labib, Karim

Journal:

Current Biology

Year:

2013

Language:

english

File:

PDF, 1.93 MB

english, 2013

25

Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation

van Deursen, Frederick, Sengupta, Sugopa, De Piccoli, Giacomo, Sanchez-Diaz, Alberto, Labib, Karim

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 1005 KB

english, 2012

26

The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth

Sanchez-Diaz, Alberto, Nkosi, Pedro Junior, Murray, Stephen, Labib, Karim

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

27

Building a double hexamer of DNA helicase at eukaryotic replication origins

Journal:

The EMBO Journal

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

28

A conserved Polϵ binding module in Ctf18-RFC is required for S-phase checkpoint activation downstream of Mec1

García-Rodríguez, Luis J., De Piccoli, Giacomo, Marchesi, Vanessa, Jones, Richard C., Edmondson, Ricky D., Labib, Karim

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

29

Tethering of SCFDia2 to the Replisome Promotes Efficient Ubiquitylation and Disassembly of the CMG Helicase

Maculins, Timurs, Nkosi, Pedro Junior, Nishikawa, Hiroko, Labib, Karim

Journal:

Current Biology

Year:

2015

Language:

english

File:

PDF, 2.05 MB

english, 2015

30

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C. elegans Embryos

Sonneville, Remi, Craig, Gillian, Labib, Karim, Gartner, Anton, Blow, J. Julian

Journal:

Year:

2015

Language:

english

File:

PDF, 3.90 MB

english, 2015

31

MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes

Abdul Rehman, Syed Arif, Kristariyanto, Yosua Adi, Choi, Soo-Youn, Nkosi, Pedro Junior, Weidlich, Simone, Labib, Karim, Hofmann, Kay, Kulathu, Yogesh

Journal:

Year:

2016

Language:

english

File:

PDF, 3.44 MB

english, 2016

32

The cell cycle || Surviving chromosome replication: the many roles of the S-phase checkpoint pathway

Karim Labib and Giacomo De Piccoli

Journal:

Philosophical Transactions Biological Sciences

Year:

2011

Language:

english

File:

PDF, 1.52 MB

english, 2011

33

Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase

Villa, Fabrizio, Simon, Aline C., Ortiz Bazan, Maria Angeles, Kilkenny, Mairi L., Wirthensohn, David, Wightman, Mel, Matak-Vinkovíc, Dijana, Pellegrini, Luca, Labib, Karim

Journal:

Year:

2016

Language:

english

File:

PDF, 4.92 MB

english, 2016

34

CUL-2LRR-1 and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis

Sonneville, Remi, Moreno, Sara Priego, Knebel, Axel, Johnson, Clare, Hastie, C. James, Gartner, Anton, Gambus, Agnieszka, Labib, Karim

Journal:

Nature Cell Biology

Year:

2017

Language:

english

File:

PDF, 10.71 MB

english, 2017

35

Ufd1-Npl4 Recruit Cdc48 for Disassembly of Ubiquitylated CMG Helicase at the End of Chromosome Replication

Maric, Marija, Mukherjee, Progya, Tatham, Michael H., Hay, Ronald, Labib, Karim

Journal:

Year:

2017

Language:

english

File:

PDF, 2.91 MB

english, 2017

36

Targeting the genome stability hub Ctf4 by stapled-peptide design

Wu, Yuteng, Villa, Fabrizio, Maman, Joseph, Dobnikar, Lina, Lau, Yu H, Simon, Aline C, Labib, Karim, Spring, David R, Pellegrini, Luca

Journal:

Angewandte Chemie

Year:

2017

Language:

english

File:

PDF, 3.14 MB

english, 2017

37

LEM-3 is a midbody-tethered DNA nuclease that resolves chromatin bridges during late mitosis

Hong, Ye, Sonneville, Remi, Wang, Bin, Scheidt, Viktor, Meier, Bettina, Woglar, Alexander, Demetriou, Sarah, Labib, Karim, Jantsch, Verena, Gartner, Anton

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 5.50 MB

english, 2018

38

Hof1 and Rvs167 Have Redundant Roles in Actomyosin Ring Function during Cytokinesis in Budding Yeast

Nkosi, Pedro Junior, Targosz, Bianca-Sabrina, Labib, Karim, Sanchez-Diaz, Alberto, Aspenstrom, Pontus

Journal:

Year:

2013

Language:

english

File:

PDF, 3.65 MB

english, 2013

39

Effect of the Mode of Application of Cryopreserved Human Amniotic Membrane on Adhesion Formation after Abdomino-Pelvic Surgery in a Mouse Model

Nassif, Joseph, Abbasi, Sehrish A., Kechli, Mohamad Karim, Boutary, Suzan S., Ghulmiyyah, Labib, Khalifeh, Ibrahim, Abou Ghaddara, Hussein, Nassar, Anwar H.

Journal:

Frontiers in Medicine

Year:

2016

Language:

english

File:

PDF, 1.18 MB

english, 2016

40

Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study

Meshaal, Marwa Sayed, Labib, Dina, Said, Karim, Hosny, Mohammed, Hassan, Mohammed, Abd Al Aziz, Said, Elkholy, Amani, Anani, Mervat, Rizk, Hussien, Ballotta, Andrea

Journal:

Year:

2018

Language:

english

File:

PDF, 6.21 MB

english, 2018

41

Histone H2A‐H2B binding by Pol α in the eukaryotic replisome contributes to the maintenance of repressive chromatin

Evrin, Cecile, Maman, Joseph D, Diamante, Aurora, Pellegrini, Luca, Labib, Karim

Journal:

The EMBO Journal

Year:

2018

Language:

english

File:

PDF, 1.53 MB

english, 2018

42

The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans

Hong, Ye, Velkova, Maria, Silva, Nicola, Jagut, Marlène, Scheidt, Viktor, Labib, Karim, Jantsch, Verena, Gartner, Anton, Engebrecht, JoAnne

Journal:

Year:

2018

Language:

english

File:

PDF, 10.57 MB

english, 2018

43

The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands

Gan, Haiyun, Serra-Cardona, Albert, Hua, Xu, Zhou, Hui, Labib, Karim, Yu, Chuanhe, Zhang, Zhiguo

Journal:

Year:

2018

Language:

english

File:

PDF, 5.04 MB

english, 2018

44

Correction: Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study

Meshaal, Marwa Sayed, Labib, Dina, Said, Karim, Hosny, Mohammed, Hassan, Mohammed, Abd Al Aziz, Said, Elkholy, Amani, Anani, Mervat, Rizk, Hussien

Journal:

Year:

2018

Language:

english

File:

PDF, 212 KB

english, 2018

45

Correction: Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study

Meshaal, Marwa Sayed, Labib, Dina, Said, Karim, Hosny, Mohammed, Hassan, Mohammed, Abd Al Aziz, Said, Elkholy, Amani, Anani, Mervat, Rizk, Hussien

Journal:

Year:

2018

Language:

english

File:

PDF, 176 KB

english, 2018

46

Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements

Deng, Lin, Wu, R. Alex, Sonneville, Remi, Kochenova, Olga V., Labib, Karim, Pellman, David, Walter, Johannes C.

Journal:

Year:

2019

File:

PDF, 4.49 MB

2019

47

Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements

Deng, Lin, Wu, R. Alex, Sonneville, Remi, Kochenova, Olga V., Labib, Karim, Pellman, David, Walter, Johannes C.

Journal:

Year:

2019

Language:

english

File:

PDF, 4.49 MB

english, 2019

48

In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast

Mukherjee, Progya P., Labib, Karim P.M.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.60 MB

english, 2019

49

In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast

Mukherjee, Progya P., Labib, Karim P.M.

Journal:

Year:

2019

File:

PDF, 2.60 MB

2019